Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p338 | (1) | WCRB2014

Gonadotropin-independent follicle development in the Kiss1/− female rats

Shirota Mariko , Kawashima Jun , Shirota Kinji , Uenoyama Yoshihisa , Nakamura Sho , Ikegami Kana , Maeda Kei-ichiro , Tsukamura Hiroko

Introduction: Kisspeptin, encoded by Kiss1, is a neuropeptide that directly regulates GnRH secretion from the hypothalamus. The present study aimed to examine a relationship between the circulating gonadotropin levels and follicle development using the Kiss1 knockout (Kiss1 KO) adult female rats.Materials and methods: Kiss1 KO and WT animals were obtained by mating of Kiss1+/− males and female...